Granulomatous slack skin presenting as diffuse poikiloderma and necrotic ulcers, with features of granulomatous vasculitis and response to oral prednisone, acitretin, and oral psoralen plus ultraviolet light therapy—A case report

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Granulomatous slack skin presenting as diffuse poikiloderma and necrotic ulcers, with features of granulomatous vasculitis and response to oral prednisone, acitretin, and oral psoralen plus ultraviolet light therapy—A case report

GSS: granulomatous slack skin PUVA: psoralen plus ultraviolet A therapy INTRODUCTION Granulomatous slack skin (GSS), a rare variant of mycosis fungoides, is characterized clinically by bulky, pendulous skin folds on flexural areas and histologically by elastolytic granulomatous infiltrates of clonal T cells. The monoclonal rearrangement of the T-cell receptor b and g genes can be demonstrated b...

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Granulomatous slack skin.

Granulomatous slack skin is an extremely uncommon form of cutaneous T-cell lymphoma. We report a case occurring in a 29-year-old man, who had generalized, progressive skin lesions evolving to nodular swellings and folds in the flexural regions, and peripheral blood and marrow involvement. The biopsies were initially misinterpreted as xanthogranuloma or granulomatous inflammation. Histologically...

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Slack Skin Syndrome with Granulomatous Involvement of the Lungs: A Case Report and Literature Review

Granulomatous slack skin syndrome is a rare variant of mycosis fugoides characterized by the development of pendulous skin folds in the intertriginous regions. It has an indolent but progressive course and is usually refractory to treatment. Extra-cutaneous involvement is rare. We report a unique case of slack skin syndrome coexisting with a progressive granulomatous lung disease.

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Effective oral psoralen plus ultraviolet a therapy for digital ulcers with revascularization in systemic sclerosis.

Systemic sclerosis (SSc) is a heterogeneous disorder characterized by excessive fibrosis and microvascular damage to the skin and various internal organs, including the lungs, kidneys, oesophagus and heart. Raynaud’s phenomenon is an almost universal symptom of SSc; 95% of patients are affected. Digital ulcers are observed frequently, especially in intractable cases with severe Raynaud’s phenom...

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ژورنال

عنوان ژورنال: JAAD Case Reports

سال: 2017

ISSN: 2352-5126

DOI: 10.1016/j.jdcr.2017.03.012